Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | INOH_NOTCH SECRETORY PATHWAY |
| Enrichment Score (ES) | -0.685424 |
| Normalized Enrichment Score (NES) | -1.5823015 |
| Nominal p-value | 0.014644352 |
| FDR q-value | 0.2030316 |
| FWER p-Value | 0.978 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAML1 | 2760008 | 1212 | 0.928 | -0.0121 | No | ||
| 2 | CREBBP | 5690035 7040050 | 1393 | 0.828 | 0.0256 | No | ||
| 3 | LFNG | 5360711 | 2028 | 0.557 | 0.0234 | No | ||
| 4 | ADAM17 | 360292 | 3194 | 0.257 | -0.0246 | No | ||
| 5 | FURIN | 4120168 | 3599 | 0.199 | -0.0349 | No | ||
| 6 | DLL1 | 1770377 | 4085 | 0.150 | -0.0524 | No | ||
| 7 | RBPJ | 2360164 5550136 5720402 | 4358 | 0.130 | -0.0596 | No | ||
| 8 | NUMB | 2450735 3800253 6350040 | 5296 | 0.081 | -0.1054 | No | ||
| 9 | MFNG | 1770242 4280348 | 5849 | 0.063 | -0.1314 | No | ||
| 10 | JAG2 | 1500341 | 6981 | 0.036 | -0.1902 | No | ||
| 11 | JAG1 | 3440390 | 7720 | 0.024 | -0.2285 | No | ||
| 12 | ADAM10 | 3780156 | 8259 | 0.015 | -0.2566 | No | ||
| 13 | DLL3 | 4010093 | 8790 | 0.008 | -0.2846 | No | ||
| 14 | DLL4 | 6400403 | 10363 | -0.014 | -0.3684 | No | ||
| 15 | NOTCH2 | 2570397 | 13110 | -0.074 | -0.5119 | No | ||
| 16 | PSEN2 | 130382 | 14880 | -0.186 | -0.5964 | No | ||
| 17 | FBXW7 | 4210338 7050280 | 14925 | -0.190 | -0.5879 | No | ||
| 18 | RFNG | 6290086 | 15337 | -0.242 | -0.5962 | No | ||
| 19 | NOTCH4 | 2450040 6370707 | 15368 | -0.246 | -0.5837 | No | ||
| 20 | ITCH | 1410731 5700022 | 15384 | -0.248 | -0.5703 | No | ||
| 21 | DTX2 | 4210041 7000008 | 17525 | -0.904 | -0.6337 | Yes | ||
| 22 | PSEN1 | 130403 2030647 6100603 | 17694 | -0.996 | -0.5857 | Yes | ||
| 23 | DTX3 | 1690458 | 18276 | -1.524 | -0.5297 | Yes | ||
| 24 | DTX1 | 5900372 | 18521 | -2.127 | -0.4211 | Yes | ||
| 25 | NOTCH3 | 3060603 | 18565 | -2.482 | -0.2813 | Yes | ||
| 26 | NOTCH1 | 3390114 | 18616 | -4.962 | -0.0000 | Yes |
